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BIO-15 Natural Probiotics


BIO-15 Probiotics - BIOe Online
BIO-15 Probiotics - BIOe Online
BIO-15 Probiotics - BIOe Online
BIO-15 Probiotics - BIOe Online
BIO-15 Probiotics - BIOe Online
BIO-15 Probiotics - BIOe Online
BIO-15 Natural Probiotics
BIO-15 Natural Probiotics
BIO-15 Natural Probiotics
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Regular price $596.00 Sale price $632.00

Unit price per 

100 capsules (per box)

Enjoy the maximum benefits of our Award-winning Probiotic supplement.

BIO-15 is the first supplement that contains probiotics, prebiotics, enzymes, biogenic and supernatant. Following a 6-year natural fermentation process, this natural blend contains 180 types of fruits, herbs, vegetables, berries, mushrooms, and spring water.

Unlike regular probiotic supplements, you won’t need to consume any other supplement or prebiotic to optimize its functioning.

With 15 clinically proven live-strains you can enjoy optimal digestive and gut health. Not only does this improve your bowel system but also the energy levels, immunity, and overall health. 


  1. Naturally Fermented: BIO15 undergoes a natural fermentation process, resulting in a unique flavor profile and potential beneficial microbial content.

  2. Contains Live Cultures: BIO15 contains live, viable lactic acid bacteria, which are associated with fermented foods and may contribute to gut health.

  3. Supports Digestive Health: BIO15 may support digestive comfort and overall gastrointestinal well-being.

  4. May Boost Energy and Mental Alertness: Some individuals report feeling more energized and mentally alert after consuming BIO15.

  5. Promotes Relaxation and Healthy Cholesterol Levels: Some individuals may experience relaxation effects, and our product may support overall cardiovascular health when combined with a balanced diet and lifestyle.

  6. Natural Antioxidants for Skin Health: BIO15 contains natural compounds that act as antioxidants, which may contribute to skin health and radiance.

  7. Supports Immune Function: Some individuals find that regular consumption of BIO15 supports their immune system, potentially helping them stay healthy.

  8. May Assist with Blood Sugar Regulation: BIO15 may play a role in maintaining healthy blood sugar levels within the normal range as part of a balanced diet.

  9. Nutrient-Rich Composition: BIO15 is rich in essential nutrients, including amino acids, vitamins, minerals, and organic acids, which can contribute to overall well-being.

Product Details

The World’s first and leading Award-Winning Probiotic that employs a traditional, 100% natural fermentation process uniquely from Japan.  Resulting in highly effective, powerful all natural premium probiotic.

A full-culture production method which retains all the friendly bacteria and supernatant, which is only possible through a natural fermentation process is the most desirable method.  BIO-15 is the only Probiotic in the World that is a “super” probiotic that contains Probiotic, Prebiotic, Biogencis and Supernatant is retained.

1. The First and Only Probiotic in the world to use an all Natural, Fermentation Process of over 6 years, resulting in a full-culture method which retains all the friendly bacteria + Supernatant

2. Award Winning, Deluxe Blend of over 180 types of Organic Herbs, Berries, Plants, Mushrooms infused with Natural Mountainous Spring Water.

3. Contains Unique Formulation that includes Prebiotics + Probiotics + Biogenics

4. Special Enteric-Coated (Double-coated) Encapsulation through patented Sankyo Capsules that is vegetable based, 100% natural and is able to withstand harsh stomach acids in order to be safely delivered to the intestinal gut.

5. Only Probiotic that contains Live Viable Lactic Acid Bacteria, possible only through its 100% natural 6 years fermentation process

6. Unique Japanese fermentation technique which is able to maintain the Live Viable Lactic Acid Bacteria and hence allowing the product to be stored Without Refrigeration.

7. Developed with the Highest Standards & Strictest Quality Controls in a controlled environment, under Japan’s Health Authority & every capsule is hygienically encased in blister packs.

8. Over 180 types of Organic Herbs, Plants & Berries fermented for over 6 years.

9. Contains 15 strains of Live lactic Acid Bacteria.

BIO-15 Probiotics Pic 4

The Advantage of BIO-15 Probiotics

1. Friendly Bacteria cannot survive high heat & pressure that is inherent in many manufacturing processes. It is the reason why BIO-15™ uses the time honored & painstaking method of a 6 Year Natural Fermentation which allows for the growth, nurture & survival of Live, Viable & Stable Lactic Acid Bacteria.

2. Friendly Bacteria cannot survive stomach acids to populate both the colon & intestines, where it is needed most. BIO-15™ uses the patented enteric (Double) coating developed by Sankyo Co.; one of the leading encapsulation facilities in the world, thereby allowing it to survive stomach acidity, bile & enzymes, delivering the full benefits of BIO-15™ & Live Viable Bacteria for effective colonization in the gut. Further, the Prebiotics in BIO-15™ serve as “food” for the Friendly Bacteria to survive.

3. All Probiotics are not created equal & do not exert the same effect. As a superior, award-winning product from Japan, BIO-15™, with its unique Natural Fermentation process & painstaking attention to every detail in the product manufacture, has, through the years, proven its effectiveness & attests greatly to its ability in overcoming all the problems faced with common Probiotics & Probiotics with conventional strains. As a result, it has won numerous accolades & is greatly endorsed by leading naturopaths, herbalists, general practitioners, medical personnel & doctors globally. BIO-15™ is the only Probiotic in the World that is a “super” probiotic where the Probiotic, Prebiotic, Biogenics (Supernatant) is retained.

Extensive Awards and Accolades

Japanese Imperial Household CertificateAwards

Award for Achievements & Supplier for the Imperial Household of Japan,  GMP, Organic< JAS and Safety Certifications

Live & Viable BIO-15 Probiotics

15 clinically-proven strains of Live Lactic Acid Bacteria:

  • Bifidobacterium lactis 
    - fights tumor growth, enhances immunity and digestive conditions while reducing intestinal permeability, lactose intolerance, allergies, inflammation, total cholesterol and blood glucose levels
  • Bifidobacterium bifidum
    - reduces stress, has antioxidant properties, and improves digestive tract disorders such as diarrhea, constipation, upper and lower abdominal pain, IBS and IBD, and bloating
  • Lactobacillus acidophilus
    - reduces “bad” cholesterol, prevents/reduces diarrhea, colds, flu, eczema, allergy symptoms, vaginal infections, and irritable bowel syndrome, promotes weight loss and improves intestinal health
  • Lactobacillus acetotolerans
  • Lactobacillus casei ss. Casei
    - kills harmful microorganisms, prevents/treats diarrhea, and reduces colic, constipation, inflammatory bowel disease (IBD), irritable bowel syndrome, lactose intolerance, allergies, eczema, and infections
  • Lactobacillus fermentum
    - is an antioxidant, increases bioavailability of some minerals, lowers cholesterol and inflammation, protects the liver, and improves immunity, lactose tolerance, mood and brain function
  • Lactobacillus brevis
    - fights h. pylori that causes gastric ulcers, improves cognitive function, and boosts immunity by killing harmful microbes
  • Lactobacillus buchneri
    - kills some pathogenic microbes, improves the health of the digestive tract, reduces inflammation and relieves diarrhea
  • Lactobacillus plantarum
    - stimulates the digestive system, fights pathogenic bacteria, revs up energy and the immune system, treats or prevents hypertension, anxiety, diabetes, eczema, IBS, IBD, sharpens memory and promotes weight loss
  • Lactobacillus amylovorus
    - improves metabolism, helps with weight loss, reduces inflammation, kills harmful bacteria and fungi, and treats/prevents vaginal infections, diarrhea, and eczema
  • Leuconostoc mesenteroides
    - boosts immunity by killing disease-causing microbes and controls the influenza virus
  • Pediococcus acidilactici
    - treats constipation and diarrhea, boosts the immune system, relieves stress, and metabolic disorder problems, improves digestion of complex carbohydrates and kills pathogens
  • Pediococcus damnosus
  • Pediococcus pentosaceus
    - inhibits the growth of disease-causing bacteria such as Listeria, improves digestive enzyme activity, and lowers cholesterol
  • Pediococcus urinae equi

Prebiotics are Food Ingredients such as (FOS) that are essential & beneficial to us, as they stimulate the growth and activity of bacteria in our colon. They do this by serving as “food” for the intestinal friendly bacteria.

Biogenics (or Supernatant) also classified as Phytochemicals are the food ingredients that directly affect and regulate stress, appetite, absorption, immunity, anti-allergies, disease prevention, diarrhea, constipation, cancer, cholesterol, diabetes, as well as suppressing aging, thereby acting as an anti-aging stimulant. Additionally, assisting in suppressing mutating genes, carcinogens, oxidation processes, regulating cholesterol and purifying our intestines.

In essence, Biogenics stimulates and contribute to anti-hypertension activity, stimulates the immunity activity, cholesterol-lowering activity, controlling of the intestinal function activity and anti-tumor activity.

18 Amino Acids, 10 Vitamins, 9 Minerals & 4 Organic Acids

18 Amino Acids

10 Vitamins

9 Minerals

4 Organic Acids

  • Alanine
  • Arginine *
  • Aspartic acid
  • Cystine
  • Glutamic acid
  • Glycine
  • Histidine *
  • Isoleucine *
  • Leucine *
  • Lysine *
  • Methionine *
  • Phenylananine *
  • Proline
  • Serine
  • Threonine *
  • Tryptophan *
  • Tyrosine
  • Valine *
  • Biotin
  • Carotene
  • Folic Acid
  • Inositol
  • Niacin
  • Panthothenic acid
  • Riboflavin B2
  • Thiamin B1
  • Vitamin B6
  • Vitamin B12
  • Calcium
  • Iron
  • Magnesium
  • Manganese
  • Phosphorus
  • Potassium
  • Sodium
  • Zinc
  • Boron
  • Acetic Acid
  • Formic Acid
  • Fumaric Acid
  • Lactic Acid


10 out of the 18 Amino Acids are essentials amino acids marked with an Asterisk *


Other by-products like hydrogen peroxide (which is anti-microbial) and natural antibiotics are also produced



Ingredients in BIO-15 Probiotics

Fermented, Organic, Non-GMO & Predigested!

It’s ONLY through our tedious natural fermentation that our ingredients Provides Full absorption of nutrients to your body!

With over 180 types of Organic Plants, herbs, berries & mushrooms used in the making of the BIO-15™ paste, here are SOME of them.

Blueberries contain high levels of Iron, Vitamin C & E, Anthocyanins, Antioxidant pigments & various phytochemicals that have a role in reducing risks of some diseases including cancers.

Green Tea has high levels of Polyphenols & other Antioxidants to improve cardiovascular health. Seaweed is rich in Iodine. It has been asserted that seaweeds may have curative properties for tuberculosis, arthritis, colds & even tumors.

Agaricus Mushrooms – 3 types of anti-cancer drugs are produced from mushrooms to help rid & fight against cancer by helping to strengthen the immune system. (Immunotherapy). We use several types including Blazei Murill – University of Tokyo Medical Dept, the National Cancer Research Center & Tokyo College of Pharmacy, supports the anti-cancer effectiveness of blazei murill mushrooms having 4 Times that of REISHI, a mushroom long used for aiding cancer prevention.

Maitake – Maitake Mushroom may best be known for its cancer-fighting properties. It also has the ability to regulate blood pressure, glucose, both serum & liver lipids, such as cholesterol, triglycerides & phospholipids.

Shiitake is used for their medicinal benefits mainly anti-tumor properties. Contain polysaccharide lentinan, α (1-3) β-D-glucan, responsible for the anti-tumor effects. Soya Bean contain high amounts of protein, including all of the essential amino acids (the only such vegetable source). It promotes heart health, prevention of cancer & alleviating menopausal symptoms.

Japanese Mountain Ginseng stimulates the formation of blood vessel & improves blood circulation in the brains, thereby improving memory & cognitive abilities. Ginseng is also used for diabetes, migraine, infections, radiation & chemotherapy protection, to aid in sleep & to stimulate the appetite.

Ume (Japanese Plum) – In clinical trials, Ume had proven extremely effective in helping improve circulation in elderly Japanese subjects. In addition to being a highly concentrated source of natural citric acid, minerals & the health-giving properties of Ume, Ume is without question one of the most highly alkalizing supplements on earth.

Prune contains the Natural Laxative Dihydrophenylisatin, Dietary Fibre & high Antioxidant content.

Turmeric is one of nature’s most powerful healers. Long known for its anti-inflammatory properties, recent research has revealed that turmeric is a natural wonder, proving beneficial in the treatment of many different health conditions from cancer to Alzheimer’s disease.

Figs have one of the highest plant sources of Calcium & Fibre. According to USDA data, dried figs are richest in Fibre, Copper, Manganese, Magnesium, Potassium, Calcium, & Vitamin K, high in Antioxidants & a good source of Flavonoids & Polyphenols.

Citron is used mainly for medical purposes: to combat against seasickness, pulmonary troubles, intestinal ailments. The essential oil is also regarded as a Natural Antibiotic. Wakame is a rich source of EPA, an ω-3 essential fatty acid. Wakame also has high levels of Calcium, Iodine, Thiamine & Niacin.

Kombu naturally contains Glutamic Acid, an Amino Acid.

Rice Bran – Phytonutrients from rice bran have shown promising disease-preventing & health-related benefits. These compounds may benefit conditions including cancer, hyperlipidemia, fatty liver, hypercalciuria, kidney stones & heart disease.

& many more…

Dosage + Info

Contain 100 capsules in blister packed box

For optimum health, take 2-5 capsules daily. 

To be taken once a day one hour before or after meal, with a glass of water.


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Made in japan

A trusted name for many Japanese and Asia households worldwide.

Extensive Awards & Accolades

Award for Achievement & Supplier for the Imperial Household of Japan.  GMP, Organic, JAS and Safety Certifications.

The Gold Standard of naturally fermented Probiotics - BIOGenics MD Gold Edition

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