Wellness Starts Within
A Healthier Gut. A Better You.
Good health begins with a balanced gut. BIO-15 brings together the goodness of Japanese natural fermentation, live probiotic cultures and beneficial nutrients to support digestive health and everyday wellbeing.
Discover a more complete approach to gut wellness, naturally.
Award-Winning Japanese Quality. More Than Just Probiotics.
BIO-15 is a premium Japanese probiotic formulation combining 15 strains of live lactic acid bacteria, prebiotics and BIOGenics with the goodness of over 180 botanical ingredients naturally fermented for six years.
What makes BIO-15 different is its distinctive six-year, full-culture fermentation process, which retains both live lactic acid bacteria and the supernatant — the liquid portion of the fermented culture containing soluble fermentation-derived substances.
Together with prebiotics and BIOGenics, this creates a more comprehensive formulation that goes beyond conventional probiotics.
Why Choose BIO-15?
- 6-in-1 Complete Gut Wellness — A distinctive combination of prebiotics, probiotics, BIOGenics, biofilm, enzymes and nutrients.
- Six Years of Natural Fermentation — Over 180 botanical ingredients undergo a prolonged Japanese fermentation process.
- Full-Culture Goodness — Retains live probiotic cultures together with beneficial fermentation-derived components.
- Advanced Capsule Protection — Vegetable-based, enteric-coated capsules designed to protect their contents through the stomach.
- Japanese Quality & Convenience — Individually sealed capsules that can be stored without refrigeration, according to product instructions.
More Than Probiotics. The Goodness of Japanese Fermentation in Every Capsule.
The Hallmarks of BIO-15 Quality
Japanese Quality. Natural Ingredients. Uncompromising Standards.
Real Experiences. Everyday Wellness.
I have been taking BIO15 for more than 6 years and it has been a game changer for my gut health. I used to experience bloatedness after meals. That is no longer the case.
John W.
21 Jan 2022 · Long-term Customer
Consume 4 per day in the morning. Effortless daily bowel movements, sometimes twice a day. Digestion seems a lot better. Feel lighter probably because the bloatedness is gone.
Susan A.
10 Aug 2023 · Digestive Wellness
The taking of BIO15 Natural probiotics has improved the health of my digestive tract. I find myself more attentive and energetic in the day. It improves my complexion too.
Goh H.
3 Dec 2021 · Energy and complexion
Used to have frequent stomach aches and discomfort. After taking BIO15 probiotics product, I rarely had such bad experiences. It really helps a lot. I trust this product.
Vincent K.
18 Jul 2022 · Digestive comfort
I used to have irregular bowel movements, sometimes not clearing my bowels for a whole week. After taking BIO15, the symptoms have improved greatly and I clear my bowels once a day. I feel lighter now.
Fion L.
31 Aug 2020 · Bowel regularity
The Power of 6-in-1 Gut Wellness
Six Essential Components. One Complete Japanese Formulation.
BIO-15 goes beyond conventional probiotics by combining live beneficial cultures with prebiotics and fermentation-derived components.
Its distinctive 6-in-1 formulation brings together:
- Prebiotics — Nourishment that supports beneficial gut bacteria.
- 15 Probiotic Strains — Live lactic acid bacteria that help maintain intestinal microbial balance.
- BIOGenics — Beneficial fermentation-derived components that complement the live cultures.
- Biofilm — A component associated with the full-culture fermentation process.
- Enzymes — Naturally occurring fermentation-derived enzymes.
- Nutrients — A rich blend of amino acids, vitamins, minerals and organic acids.
More Than Just Probiotics. A More Complete Approach to Gut Wellness.
6 Years of Natural Fermentation
180+ Botanical Ingredients. Six Years of Patience. One Exceptional Formulation.
Inspired by Japan's longstanding fermentation traditions, BIO-15 is crafted through a meticulous six-year natural fermentation process using more than 180 botanical ingredients, including herbs, plants, berries and mushrooms.
At the heart of BIO-15 is its full-culture fermentation method, designed to retain both the live beneficial bacteria and the supernatant rather than separating them during production.
The supernatant contains soluble substances produced or released during fermentation, contributing to BIO-15's distinctive combination of probiotic cultures and fermentation-derived components.
The result is a distinctive combination of probiotic cultures, BIOGenics, enzymes and naturally occurring nutrients.
Naturally Fermented. Thoughtfully Crafted. Distinctively Japanese.
A “super” probiotic
The World’s first and leading Award-Winning Probiotic that employs a traditional, 100% natural fermentation process uniquely from Japan. Resulting in highly effective, powerful all natural premium probiotic.
Digestive Health
~ Feel comfortable after meals ~
BIO15’s naturally fermented live cultures and enzymes support digestion, digestive comfort and the absorption of nutrients as part of a balanced diet
Gut Balance
~ Maintain a healthier intestinal environment ~
15 listed lactic-acid bacteria species and subspecies, supported by FOS prebiotics, help maintain beneficial intestinal bacteria and a balanced gut environment
Bowel Regularity
~ Keep your bowel movements regular ~
Irregular bowel movements can be accompanied by bloating and discomfort. BIO15 supports bowel regularity and gastrointestinal well-being as part of your daily routine
Immune System
~ Support your body's everyday defences ~
A balanced gut plays a role in overall wellness. BIO15 provides daily immune support through its fermented cultures and plant-based ingredients
Beautiful Skin
~ Care for your complexion from within ~
Naturally occurring antioxidants and fermentation-derived nutrients support healthy looking complexion, glow from within
Energy & Vitality
~ Be ready for an active day ~
More than 180 fermented plant-based ingredients provide a rich blend of amino acids, vitamins, minerals and other nutrients to help nourish your body each day
History Behind the Legend
Bringing you 200 years of Traditional Japanese Herbal Know-how. The Award-winning Symbiotic.
Founded during the 1690s, through the Tokugawa Shogunate in 1790s, from feudal lords, daimios, famous kabuki stars and to the present day Japanese Imperial Household,
Learn more about the bio15 probiotic
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Our Blog
Aug 24, 2021
Mushrooms: From Myths to Facts
Jul 19, 2021
Scientific Basis for Your Gut: 3 Ways to Improve Your Intestinal Health
Oct 16, 2020